Dr Tatiane Yanes
Postdoctoral Research Fellow
Frazer Institute
Researcher biography
Tatiane completed a Bachelor of Science (Genetics and Molecular Biology) at the Australian National University, and a Master of Genetic Counselling at Griffith University. While studying for her master's degree, Tatiane completed a placement at the National Institute of Health where she assisted in research assessing the impact of genomic testing and completed training as research genetic counsellor. Her time at the National Institute of Health sparked a love for genetic counselling research and in 2015 Tatiane moved to Sydney to complete a PhD at UNSW Sydney.
Recently, Tatiane submitted her PhD thesis where she assessed the psychological and behavioural impact of returning polygenic risk scores to women at increased risk of breast cancer. During her PhD, she was awarded a National Health and Medical Council (NHMRC) postgraduate scholarship, a National Breast Cancer Foundation scholarship and a Translational Cancer Research Network PhD top-up award. She also received multiple awards including best oral presentation at the 2017 International Meeting on Psychosocial Impact of Hereditary Cancer, and was a runner-up for best oral presentation at the 2018 Translational Cancer Research Network Symposium. On top of her research, Tatiane has also worked as a clinical and research genetic counsellor in Brisbane and Sydney.
In 2019 Tatiane returned to Brisbane and is now a postdoctoral research fellow at UQ Diamantina Institute. She continues to conduct research to support the safe implementation of polygenic risk scores into clinical practice including assessing health care professionals training needs, evaluating existing methods of communicating polygenic information, and assessing psychological and behavioural outcomes associated with receiving this information. She also recently developed a workshop to upskill genetic health professionals on the use of polygenic risk information to assess cancer risk. Given her expertise as a genetic counsellor and experience with polygenic risk scores, Tatiane has been invited to present at several national and international meetings including at the Familial Aspects of Cancer: Research and Practice, Kingscliff, Australia; the Australian Polygenic Risk Symposium, Sydney; and at the National Society of Genetic Counsellors annual conference, Salt Lake City, USA.
Journal Articles
Yanes, Tatiane, Nathan, Vaishnavi, Wallingford, Courtney, Faragher, Rhonda, Nankervis, Karen, Jacobs, Chris, Vassos, Maria, Boyle, Fran, Carroll, Annemaree, Smith, Simon and McInerney‐Leo, Aideen (2023). Australasian genetic counselors' attitudes toward disability and prenatal testing: Findings from a cross‐sectional survey. Journal of Genetic Counseling, 1-12. doi: 10.1002/jgc4.1788
Haining, Casey Michelle, Tiller, Jane, Otlowski, Margaret, Gleeson, Penny, Murawski, Carsten, Barlow-Stewart, Kristine, Lacaze, Paul, McInerney-Leo, Aideen and Keogh, Louise Anne (2023). Financial advisers’ and key informants’ perspectives on the Australian industry-led Moratorium on Genetic Tests in Life Insurance. Public Health Genomics, 26 (1), 123-134. doi: 10.1159/000533532
Yanes, Tatiane, Wallingford, Courtney, Young, Mary-Anne, McInerney-Leo, Aideen M., Willis, Amanda M., McKnight, Lauren, Terrill, Bronwyn, McInerny, Simone, Forrest, Laura E., Cicciarelli, Linda, Williams, Rachel, Keane, Holly and James, Paul A. (2023). Development and evaluation of a novel educational program for providers on the use of polygenic risk scores. Genetics in Medicine, 25 (8) 100876, 100876. doi: 10.1016/j.gim.2023.100876
Wallingford, Courtney K., Demeshko, Anastassia, Krishnakripa, Asha Krishnankutty, Smit, Darren J., Duffy, David L., Betz-Stablein, Brigid, Pflugfelder, Annette, Jagirdar, Kasturee, Holland, Elizabeth, Mann, Graham J., Primiero, Clare A., Yanes, Tatiane, Malvehy, Josep, Badenas, Cèlia, Carrera, Cristina, Aguilera, Paula, Olsen, Catherine M., Ward, Sarah V., Haass, Nikolas K., Sturm, Richard A., Puig, Susanna, Whiteman, David C., Law, Matthew H., Cust, Anne E., Potrony, Miriam, Soyer, H. Peter and McInerney-Leo, Aideen M. (2023). The MC1R r allele does not increase melanoma risk in MITF E318K carriers. British Journal of Dermatology, 188 (6), 770-776. doi: 10.1093/bjd/ljad041
Young, Mary-Anne, Yanes, Tatiane, Cust, Anne E., Dunlop, Kate, Limb, Sharne, Newson, Ainsley J., Purvis, Rebecca, Thiyagarajan, Lavvina, Scott, Rodney J., Verma, Kunal, James, Paul A. and Steinberg, Julia (2023). Human Genetics Society of Australasia position statement: use of polygenic scores in clinical practice and population health. Twin Research and Human Genetics, 26 (1), 1-9. doi: 10.1017/thg.2023.10
Yanes, Tatiane, Sullivan, Anna, Barbaro, Pasquale, Brion, Kristian, Hollway, Georgina, Peake, Jane and McNaughton, Peter (2023). Evaluation and pilot testing of a multidisciplinary model of care to mainstream genomic testing for paediatric inborn errors of immunity. European Journal of Human Genetics, 31 (10), 1-8. doi: 10.1038/s41431-023-01321-z
Umstead, Kendall L., Woolford, Samuel, Macnamara, Ellen F., Yanes, Tatiane, Brothers, Kyle B., Han, Paul K. J., Sapp, Julie C., Crenshaw, Molly, Price, Cristofer S. and Biesecker, Barbara B. (2023). Parental Uncertainty About a Child’s Health Scale (PUCHS): Development and Validation of a Novel Measure. Georgetown Medical Review, 6 (1). doi: 10.52504/001c.68103
Wand, Hannah, Kalia, Sarah S., Helm, Benjamin M., Suckiel, Sabrina A., Brockman, Deanna, Vriesen, Natalie, Goudar, Ranjit K., Austin, Jehannine and Yanes, Tatiane (2023). Clinical genetic counseling and translation considerations for polygenic scores in personalized risk assessments: a practice resource from the National Society of Genetic Counselors. Journal of Genetic Counseling, 32 (3), 558-575. doi: 10.1002/jgc4.1668
Primiero, Clare A., Finnane, Anna, Yanes, Tatiane, Peach, Betsy, Soyer, H. Peter and McInerney-Leo, Aideen M. (2022). Protocol to evaluate a pilot program to upskill clinicians in providing genetic testing for familial melanoma. PLoS One, 17 (12) e0275926, 1-15. doi: 10.1371/journal.pone.0275926
Primiero, Clare A., Baker, Amy M., Wallingford, Courtney K., Maas, Ellie J., Yanes, Tatiane, Fowles, Lindsay, Janda, Monika, Young, Mary-Anne, Nisselle, Amy, Terrill, Bronwyn, Lodge, Jason M., Tiller, Jane M., Lacaze, Paul, Andersen, Hayley, McErlean, Gemma, Turbitt, Erin, Soyer, H. Peter and McInerney-Leo, Aideen M. (2022). Attitudes of Australian dermatologists on the use of genetic testing: A cross-sectional survey with a focus on melanoma. Frontiers in Genetics, 13 919134, 1-12. doi: 10.3389/fgene.2022.919134
Lee, Katie J., Betz-Stablein, Brigid, Stark, Mitchell S., Janda, Monika, McInerney-Leo, Aideen M., Caffery, Liam J., Gillespie, Nicole, Yanes, Tatiane and Soyer, H. Peter (2022). The future of precision prevention for advanced melanoma. Frontiers in Medicine, 8 818096, 818096. doi: 10.3389/fmed.2021.818096
Wallingford, Courtney K., Kovilpillai, Hannah, Jacobs, Chris, Turbitt, Erin, Primiero, Clare A., Young, Mary-Anne, Brockman, Deanna G., Soyer, H. Peter, McInerney-Leo, Aideen M. and Yanes, Tatiane (2022). Models of communication for polygenic scores and associated psychosocial and behavioral effects on recipients: a systematic review. Genetics in Medicine, 25 (1), 1-11. doi: 10.1016/j.gim.2022.09.008
Smit, Amelia K., Sharman, Ashleigh R., Espinoza, David, Wallingford, Courtney, Young, Mary‐Anne, Dunlop, Kate, Tiller, Jane, Newson, Ainsley J., Meiser, Bettina, Cust, Anne E. and Yanes, Tatiane (2021). Knowledge, views and expectations for cancer polygenic risk testing in clinical practice: a cross‐sectional survey of health professionals. Clinical Genetics, 100 (4) cge.14025, 430-439. doi: 10.1111/cge.14025
Yanes, Tatiane, Meiser, Bettina, Kaur, Rajneesh, Young, Mary-Anne, Mitchell, Philip B., Scheepers-Joynt, Maatje, McInerny, Simone, Taylor, Shelby, Barlow-Stewart, Kristine, Antill, Yoland, Salmon, Lucinda, Smyth, Courtney, Betz-Stablein, Brigid and James, Paul A. (2021). Breast cancer polygenic risk scores: a 12-month prospective study of patient reported outcomes and risk management behavior. Genetics in Medicine, 23 (12), 2316-2323. doi: 10.1038/s41436-021-01288-6
Gregory, Gillian, Das Gupta, Kuheli, Meiser, Bettina, Barlow-Stewart, Kristine, Geelan-Small, Peter, Kaur, Rajneesh, Scheepers-Joynt, Maatje, McInerny, Simone, Taylor, Shelby, Antill, Yoland, Salmon, Lucinda, Smyth, Courtney, Young, Mary-Anne, James, Paul A and Yanes, Tatiane (2021). Polygenic risk in familial breast cancer: changing the dynamics of communicating genetic risk. Journal of Genetic Counseling, 31 (1) jgc4.1458, 120-129. doi: 10.1002/jgc4.1458
Willis, Amanda M, Smith, Sian K, Meiser, Bettina, James, Paul A, Ballinger, Mandy L, Thomas, David M, Yanes, Tatiane and Young, Mary-Anne (2021). Influence of lived experience on risk perception among women who received a breast cancer polygenic risk score: 'Another piece of the pie'. Journal of Genetic Counseling, 30 (3), 849-860. doi: 10.1002/jgc4.1384
Bakshi, Andrew, Yan, Mabel, Riaz, Moeen, Polekhina, Galina, Orchard, Suzanne G., Tiller, Jane, Wolfe, Rory, Joshi, Amit, Cao, Yin, McInerney-Leo, Aideen M., Yanes, Tatiane, Janda, Monika, Soyer, H. Peter, Cust, Anne E., Law, Matthew H., Gibbs, Peter, McLean, Catriona, Chan, Andrew T., McNeil, John J., Mar, Victoria J. and Lacaze, Paul (2021). Genomic risk score for melanoma in a prospective study of older individuals. Journal of the National Cancer Institute, 113 (10) ARTN djab076, 1379-1385. doi: 10.1093/jnci/djab076
Das Gupta, Kuheli, Gregory, Gillian, Meiser, Bettina, Kaur, Rajneesh, Scheepers-Joynt, Maatje, McInerny, Simone, Taylor, Shelby, Barlow-Stewart, Kristine, Antill, Yoland, Salmon, Lucinda, Smyth, Courtney, McInerney-Leo, Aideen, Young, Mary-Anne, James, Paul A. and Yanes, Tatiane (2021). Communicating polygenic risk scores in the familial breast cancer clinic. Patient Education and Counseling, 104 (10), 2512-2521. doi: 10.1016/j.pec.2021.02.046
Primiero, Clare A., Yanes, Tatiane, Finnane, Anna, Soyer, H. Peter and McInerney-Leo, Aideen M. (2021). A systematic review on the impact of genetic testing for familial melanoma I: primary and secondary preventative behaviours. Dermatology , 237 (5), 1-10. doi: 10.1159/000513919
Primiero, Clare A., Yanes, Tatiane, Finnane, Anna, Soyer, H. Peter and McInerney-Leo, Aideen M. (2021). A systematic review on the impact of genetic testing for familial melanoma II: psychosocial outcomes and attitudes. Dermatology, 237 (5), 1-11. doi: 10.1159/000513576
McMeniman, E. K., McInerney-Leo, A. M., Peach, E., Lee, K. J., Yanes, T., Jagirdar, K., Stark, M. S., Soyer, H. P., Duffy, D. L. and Sturm, R. A. (2020). CDKN2A testing threshold in a high-risk Australian melanoma cohort: number of primaries, family history and young age of onset impact risk. Journal of the European Academy of Dermatology and Venereology, 34 (12) jdv.16627, e797-e798. doi: 10.1111/jdv.16627
Yanes, Tatiane, McInerney-Leo, Aideen M., Law, Matthew and Cummings, Shelly (2020). The emerging field of polygenic risk scores and perspective for use in clinical care. Human Molecular Genetics, 29 (R2), R165-R176. doi: 10.1093/hmg/ddaa136
Yanes, T., Kaur, R., Meiser, B., Scheepers-Joynt, M., McInerny, S., Barlow-Stewart, K., Antill, Y., Salmon, L., Smyth, C., James, P. A. and Young, M. A. (2020). Women’s responses and understanding of polygenic breast cancer risk information. Familial Cancer, 19 (4), 297-306. doi: 10.1007/s10689-020-00185-2
Meiser, Bettina, Guo, Xin Y., Putt, Sophie, Fullerton, Janice M., Schofield, Peter R., Mitchell, Philip B. and Yanes, Tatiane (2020). Psychosocial implications of living with familial risk of a psychiatric disorder and attitudes to psychiatric genetic testing: A systematic review of the literature. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 183 (5) ajmg.b.32786, 277-288. doi: 10.1002/ajmg.b.32786
Putt, Sophie, Yanes, Tatiane, Meiser, Bettina, Kaur, Rajneesh, Fullerton, Janice M., Barlow-Stewart, Kristine, Schofield, Peter R., Toma, Claudio, Peay, Holly and Mitchell, Philip B. (2020). Exploration of experiences with and understanding of polygenic risk scores for bipolar disorder. Journal of Affective Disorders, 265, 342-350. doi: 10.1016/j.jad.2020.01.037
Yanes, Tatiane, Meiser, Bettina, Kaur, Rajneesh, Scheepers‐Joynt, Maatje, McInerny, Simone, Taylor, Shelby, Barlow‐Stewart, Kristine, Antill, Yoland, Salmon, Lucinda, Smyth, Courtney, Young, Mary‐Anne and James, Paul A. (2020). Uptake of polygenic risk information among women at increased risk of breast cancer. Clinical Genetics, 97 (3) cge.13687, 492-501. doi: 10.1111/cge.13687
Yanes, Tatiane, Young, Mary-Anne, Meiser, Bettina and James, Paul A. (2020). Clinical applications of polygenic breast cancer risk: a critical review and perspectives of an emerging field. Breast Cancer Research, 22 (1) 21, 21. doi: 10.1186/s13058-020-01260-3
Kaur, Rajneesh, Meiser, Bettina, Yanes, Tatiane, Young, Mary-Anne, Barlow-Stewart, Kristine, Roscioli, Tony, Smith, Sian and James, Paul A. (2019). Development and pilot testing of a leaflet informing women with breast cancer about genomic testing for polygenic risk. Familial Cancer, 18 (2), 147-152. doi: 10.1007/s10689-018-0104-4
Yanes, Tatiane, Willis, Amanda M., Meiser, Bettina, Tucker, Katherine M. and Best, Megan (2019). Psychosocial and behavioral outcomes of genomic testing in cancer: a systematic review. European Journal of Human Genetics, 27 (1), 28-35. doi: 10.1038/s41431-018-0257-5
Smith, Sian Karen, Cai, Antonia, Wong, Michelle, Sousa, Mariana S., Peate, Michelle, Welsh, Alec, Meiser, Bettina, Kaur, Rajneesh, Halliday, Jane, Lewis, Sharon, Trevena, Lyndal, Yanes, Tatiane, Barlow-Stewart, Kristine and Barclay, Margot (2018). Improving women's knowledge about prenatal screening in the era of non-invasive prenatal testing for Down syndrome - development and acceptability of a low literacy decision aid. BMC Pregnancy and Childbirth, 18 (1) 499. doi: 10.1186/s12884-018-2135-0
Hedelund Lausen, Lisa, Smith, Sian K., Cai, Antonia, Meiser, Bettina, Yanes, Tatiane, Ahmad, Raghib and Rowlands, Gillian (2018). How is health literacy addressed in primary care? Strategies that general practitioners use to support patients. Journal of Communication in Healthcare, 11 (4), 278-287. doi: 10.1080/17538068.2018.1531477
Yanes, Tatiane, Meiser, Bettina, Young, Mary-Anne, Kaur, Rajneesh, Mitchell, Gillian, Barlow-Stewart, Kristine, Roscioli, Tony, Halliday, Jane and James, Paul (2017). Psychosocial and behavioral impact of breast cancer risk assessed by testing for common risk variants: protocol of a prospective study. BMC Cancer, 17 (1) 491, 491. doi: 10.1186/s12885-017-3485-0
Yanes, Tatiane, Humphreys, Linda, McInerney-Leo, Aideen and Biesecker, Barbara (2016). Factors associated with parental adaptation to children with an undiagnosed medical condition. Journal of Genetic Counseling, 26 (4), 1-12. doi: 10.1007/s10897-016-0060-9
Jamal, Leila, Sapp, Julie C., Lewis, Katie, Yanes, Tatiane, Facio, Flavia M., Biesecker, Leslie G. and Biesecker, Barbara B. (2014). Research participants' attitudes towards the confidentiality of genomic sequence information. European Journal of Human Genetics, 22 (8), 964-968. doi: 10.1038/ejhg.2013.276
Conference Papers
Wallingford, Courtney, Law, Matthew, Mothershaw, Adam, Acevedo, Astrid Rodriguez, Soyer, Hans Peter, McInerney-Leo, Aideen and Yanes, Tatiane (2024). Evaluating a protocol for communicating melanoma personalised risk scores: a pilot study. 56th Annual Conference of the European-Society-of-Human-Genetics (ESHG), Glasgow, Scotland, 10-13 June 2023. London, United Kingdom: Nature Publishing Group.
Wallingford, Courtney, Kovilpillai, Hannah, Jacobs, Chris, Turbitt, Erin, Primiero, Clare, Brockman, Deanna, Soyer, Hans Peter, McInerney-Leo, Aideen and Yanes, Tatiane (2023). Models of communication for polygenic scores and associated behavioural and psychological outcomes: a systematic review. 55th European Society of Human Genetics (ESHG) Conference, Vienna, Austria, 11-14 June 2022. London, United Kingdom: Nature Publishing Group.
Yanes, Tatiane, Sullivan, Anna, Barbaro, Pasquale, Brion, Kristian, Peake, Jane and McNaughton, Peter (2023). Mainstreaming genomic testing for children with undiagnosed inborn errors of immunity. 55th European-Society-of-Human-Genetics (ESHG) Conference, Vienna Austria, Jun 11-14, 2022. LONDON: SPRINGERNATURE.
Yanes, T., Kaur, R., Meiser, B., Scheepers-Joynt, M., McInerny, S., Barlow-Stewart, K., Antill, Y., Salmon, L., Smyth, C., Halliday, J., James, P. and Young, M. (2019). High-risk women's responses and understanding of polygenic breast cancer risk information. 52nd Conference of the European-Society-of-Human-Genetics (ESHG), Gothenburg, Sweden, 15-18 June 2019 . London, United Kingdom: Nature Publishing Group.
Yanes, T., Meiser, B., Kaur, R., Scheepers-Joynt, M., Young, M., Barlow-Stewart, K., John, T., Harris, M., Antill, Y., Halliday, J., Burke, J., Roscioli, T., Mitchell, P. and James, P. (2019). Uptake of polygenic risk information among women at potentially high breast cancer risk. 51st Conference of the European-Society-of-Human-Genetics (ESHG) in conjunction with the European Meeting on Psychosocial Aspects of Genetics (EMPAG), Milan, Italy, 16-19 June 2018. London, United Kingdom: Nature Publishing Group.
Yanes, Tatiane, Meiser, Bettina, Kaur, Rajneesh, Scheepers-Joynt, Maatje, Young, Mary-Anne, Barlow-Stewart, Kristine, John, Tom, Harris, Marrion, Antill, Yoland, Burke, Jo, Roscioli, Tony, Halliday, Jane, Mitchell, Phillip and James, Paul A (2018). Polygenic breast cancer risk: A prospective study of uptake and outcomes among high-risk women. 42nd Human Genetics Society of Australasia Annual Scientific Meeting, Sydney, NSW, Australia, 4-7th August 2018. Cambridge, United Kingdom: Cambridge University Press.