Journal Articles
Wong, H., Lee, R., Roy, E., Kapadia, S., Murigneux, V., Chong, S., Freeman, M. and Khosrotehrani, K. (2022). 435 Epidermal ablation reduces keratinocyte cancer burden by lowering skin mutation load. Journal of Investigative Dermatology, 142 (12), S255. doi: 10.1016/j.jid.2022.09.449
Lee, R., Wong, H., Brown, S., Roy, E. and Khosrotehrani, K. (2022). 490 Variation in epidermal mutation burden after field treatment with topical 5-fluorouracil. Journal of Investigative Dermatology, 142 (12), S265. doi: 10.1016/j.jid.2022.09.504
Chong, Sharene, Wong, Ho Yi, Althabteh, Ahmad, Cox, Charlotte, Stevenson, Paul H., Brown, Susan, Griffin, Anthony, Isbel, Nicole, Siller, Gregory, Soyer, H. Peter, Schaider, Helmut, Roy, Edwige, Campbell, Scott, Green, Adele C. and Khosrotehrani, Kiarash (2022). Chemoprevention of cutaneous squamous cell carcinoma and its precursors in solid organ transplant recipients using topical sirolimus: a randomized, double-blind, placebo-controlled pilot trial. Journal of the American Academy of Dermatology, 87 (5), 1163-1166. doi: 10.1016/j.jaad.2022.02.039
Zhao, Jilai, Patel, Jatin, Kaur, Simranpreet, Sim, Seen-Ling, Wong, Ho Yi, Styke, Cassandra, Hogan, Isabella, Kahler, Sam, Hamilton, Hamish, Wadlow, Racheal, Dight, James, Hashemi, Ghazaleh, Sormani, Laura, Roy, Edwige, Yoder, Mervin C., Francois, Mathias and Khosrotehrani, Kiarash (2021). Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors. Nature Communications, 12 (1) 2564, 1-17. doi: 10.1038/s41467-021-22717-9
Wong, Ho Yi, Khosrotehrani, Kiarash and Roy, Edwige (2021). Whole-mount staining coupled to a UV-inducible basal cell carcinoma murine model. STAR protocols, 2 (1) 100329, 100329. doi: 10.1016/j.xpro.2021.100329
Roy, Edwige, Wong, Ho Yi, Villani, Rehan, Rouille, Thomas, Salik, Basit, Sim, Seen Ling, Murigneux, Valentine, Stark, Mitchell S., Fink, J. Lynn, Soyer, H. Peter, Walker, Graeme, Lyons, J. Guy, Saunders, Nicholas and Khosrotehrani, Kiarash (2020). Regional Variation in Epidermal Susceptibility to UV-Induced Carcinogenesis Reflects Proliferative Activity of Epidermal Progenitors. Cell Reports, 31 (9) 107702, 107702. doi: 10.1016/j.celrep.2020.107702
Lukowski, Samuel W., Patel, Jatin, Andersen, Stacey B., Sim, Seen-Ling, Wong, Ho Yi, Tay, Joshua, Winkler, Ingrid, Powell, Joseph E. and Khosrotehrani, Kiarash (2019). Single-cell transcriptional profiling of aortic endothelium identifies a hierarchy from endovascular progenitors to differentiated cells. Cell Reports, 27 (9), 2748-2758. doi: 10.1016/j.celrep.2019.04.102
Donovan, Prudence, Patel, Jatin, Dight, James, Wong, Ho Yi, Sim, Seen-Ling, Murigneux, Valentine, Francois, Mathias and Khosrotehrani, Kiarash (2019). Endovascular progenitors infiltrate melanomas and differentiate towards a variety of vascular beds promoting tumor metastasis. Nature Communications, 10 (1) 18, 18. doi: 10.1038/s41467-018-07961-w
Legrand, Julien M. D., Roy, Edwige, Baz, Batoul, Mukhopadhyay, Pamela, Wong, Ho Yi, Ram, Ramesh, Morahan, Grant, Walker, Graeme and Khosrotehrani, Kiarash (2018). Genetic variation in the MAPK/ERK pathway affects contact hypersensitivity responses. Journal of Allergy and Clinical Immunology, 142 (3), 981-984.e7. doi: 10.1016/j.jaci.2018.04.028
Chhabra, Y., Wong, H. Y., Nikolajsen, L. F., Steinocher, H., Papadopulos, A., Tunny, K. A., Meunier, F. A., Smith, A. G., Kragelund, B. B., Brooks, A. J. and Waters, M. J. (2018). A growth hormone receptor SNP promotes lung cancer by impairment of SOCS2-mediated degradation. Oncogene, 37 (4), 489-501. doi: 10.1038/onc.2017.352
Patel, Jatin, Baz, Betoul, Wong, Ho Yi, Lee, James S. and Khosrotehrani, Kiarash (2017). Accelerated Endothelial to Mesenchymal Transition increased fibrosis via deleting Notch signalling in wound vasculature. The Journal of Investigative Dermatology, 138 (5), 1166-1175. doi: 10.1016/j.jid.2017.12.004
Villani, Rehan, Hodgson, Samantha, Legrand, Julien, Greaney, Jessica, Wong, Ho Yi, Pichol-Thievend, Cathy, Adolphe, Christelle, Wainwight, Brandon, Francois, Mathias and Khosrotehrani, Kiarash (2017). Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types. Development, 144 (10), 1887-1895. doi: 10.1242/dev.143917
Patel, Jatin, Seppanen, Elke J., Rodero, Mathieu, Wong, Ho Yi, Donovan, Prudence, Neufeld, Zoltan, Fisk, Nicholas, Francois, Mathias and Khosrotehrani, Kiarash (2017). Functional definition of progenitors versus mature endothelial cells reveals key SoxF-dependent differentiation process. Circulation, 135 (8), 786-805. doi: 10.1161/CIRCULATIONAHA.116.024754
Shafiee, Abbas, Patel, Jatin, Wong, Ho Yi, Donovan, Prudence, Hutmacher, Dietmar W., Fisk, Nicholas M. and Khosrotehrani, Kiarash (2017). Priming of endothelial colony-forming cells in a mesenchymal niche improves engraftment and vasculogenic potential by initiating mesenchymal transition orchestrated by NOTCH signaling. The FASEB Journal, 31 (2), 610-624. doi: 10.1096/fj.201600937
Roy, Edwige, Neufeld, Zoltan, Cerone, Luca, Wong, Ho Yi, Hodgson, Samantha, Livet, Jean and Khosrotehrani, Kiarash (2016). Bimodal behaviour of interfollicular epidermal progenitors regulated by hair follicle position and cycling. EMBO Journal, 35 (24), 2658-2670. doi: 10.15252/embj.201693806
Patel, Jatin, Wong, Ho Yi, Wang, Weili, Alexis, Josue, Shafiee, Abbas, Stevenson, Alexander J., Gabrielli, Brian, Fisk, Nicholas M. and Khosrotehrani, Kiarash (2016). Self-renewal and high proliferative colony forming capacity of late-outgrowth endothelial progenitors is regulated by cyclin-dependent kinase inhibitors driven by notch signaling. Stem Cells, 34 (4), 902-912. doi: 10.1002/stem.2262
Conference Papers
Patel, J., Hamilton, H., Kahler, S., Sim, S., Wong, H. and Khosrotehrani, K. (2019). Changing endothelial cell fate in wound healing through modulation of Sox9 to reduce scarring. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.628
Wong, H., Roy, E., Kapadia, S., Murigneux, V., Chong, S. and Khosrotehrani, K. (2019). Laser dermabrasion: a potential treatment for non-melanoma skin cancers. 49th Annual Meeting of the European Society for Dermatological Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.567
Roy, E., Wong, H. and Khosrotehrani, K. (2019). Epidermal clonal expansion upon UV irradiation: consequences of the epidermal duality of proliferative behaviour on the skin carcinogenesis. 49th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR), Bordeaux, France, 18-21 September, 2019. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.jid.2019.07.570
Patel, J., Dight, J., Donovan, P., Wong, H. and Khosrotehrani, K. (2018). Endovascular progenitors initiate and drive de novo vascularisation in melanoma. International Investigative Dermatology (IID) Meeting, Orlando, FL United States, 16-19 May 2018. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2018.03.1255
Roy, E., Legrand, J., Baz, B., Wong, H., Morahan, G., Walker, G. and Khosrotehrani, K. (2018). Genome wide mapping identifies regulation of MAPKinase pathway as key genetic determinant of allergic contact dermatitis. International Investigative Dermatology (IID) Meeting, Orlando, FL, United States, 16 - 19 May 2018. London, United Kingdom: Nature Publishing Group.
Patel, Jatin, Seppanen, Elke J., Rodero, Mathieu, Wong, Ho Yi, Donovan, Prudence, Fisk, Nicholas M., Francois, Mathias and Khosrotehrani, Kiarash (2017). A novel in vivo endothelial hierarchy from progenitor to mature endothelial cells reveals key SoxF-dependent differentiation process. American-Heart-Association's Arteriosclerosis, Thrombosis and Vascular Biology/Peripheral Vascular Disease Scientific Sessions, Minneapolis MN, United States, 4-6 May 2017. Philadelphia, PA United States: Lippincott Williams & Wilkins.
Roy, E., Wong, H., Murigneux, V., Fink, L. and Khosrotehrani, K. (2017). Regional variation in epidermal susceptibility to ultraviolet induced carcinogenesis reflects proliferative activity of epidermal progenitors. 47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR), Salzburg Austria, 27-30 September 2017. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2017.07.721
Legrand, J., Baz, B., Mukhopadhyay, P., Wong, H., Ram, R., Morahan, G., Walker, G. and Khosrotehrani, K. (2017). Genome wide association identifies MAPKinase pathway regulators as key genetic determinants of allergic contact dermatitis. 47th Annual Meeting of the European Society for Dermatological Research (ESDR), Salzburg Austria, 27-30 September 2017. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2017.07.180
Patel, J., Baz, B., Wong, H., Lee, J. S. and Khosrotehrani, K. (2017). Deletion of Notch signalling in the vasculature accelerates Endothelial to Mesenchymal Transition in skin wound healing. 47th Annual Meeting of the European-Society-for-Dermatological-Research (ESDR), Salzburg, Austria, 27-30 September 2017. London, United Kingdom: Nature Publishing Group. doi: 10.1016/j.jid.2017.07.339
Roy, E., Neufeld, Z., Cerone, L., Wong, H. Y., Hodgson, S., Livet, J. and Khosrotehrani, K. (2016). Dual proliferation behaviour of epidermal progenitors. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12584
Roy, E., Wong, H. Y. and Khosrotehrani, K. (2016). Epidermal clonal proliferative response upon UVB irradiation is bimodal. Asia-Pacific Combined Dermatology Research Conference 2016, Noosa, QLD Australia, 25–28 August 2016. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/ajd.12584
Villani, R. M., Hodgson, S., Legrand, J., Greaney, J., Wong, H., Pichol-Thievend, C., Adolphe, C., Wainwright, B., Francois, M. and Khosrotehrani, K. (2015). Dominant negative mutation of Sox18 inhibits normal dermal papilla development during embryogenesis and regeneration. 45th Annual Meeting of the European Society for Dermatological Research, Rotterdam, Netherlands, 9-12 September 2015. London, United Kingdom: Nature Publishing Group. doi: 10.1038/jid.2015.272
Chhabra, Yash, Wong, Ho Yi, Brooks, Andrew James and Waters, Michael John (2014). The first cancer-associated variant of the growth hormone receptor. Endocrine Society's 96th Annual Meeting and Expo, Chicago, IL, United States, 21-24 June 2014. WASHINGTON: Endocrine Society.